Naloxone is a fantastic tool in reducing opioid deaths, but gentler versions would be helpful for fighting overdose ...

Naloxone, known by brand names Nyxoid or Narcan, rapidly reverses the depression of the central nervous and respiratory systems caused by opioids. It does so by attaching to the opioid receptors ...

So the way it works, and I'll try not to be too technical about this, is that we all have what's known as opioid receptors in our brains. The way that naloxone works is that it basically kicks off ...

Naloxone also attaches to opioid receptors that block the effects of other opioids in someone’s body. Naloxone is extremely effective in quickly reversing the respiratory depression of an opioid ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

Opioids can modulate endocrine processes ... This could explain how in the presence of Leu-Enk, naloxone detects a reduced number of receptors. However a two-site model is equally able to explain ...

meaning that it blocks opioids from binding the receptors without any activation. In addition, the overdose antidote naloxone can be used to treat overdose itself. It is an opioid antagonist that ...

The medication works by binding to the same receptors in the brain as opioids, countering their effects. The emerging evidence suggests how vital naloxone can be in reducing fatalities due to ...

Scientists have revealed that opioid receptors outside the brain play a key role in the hypoventilation caused by fentanyl overdoses, paving the way for better treatments. The study, forthcoming ...

Public health experts have concerns about the opioid reversal agent Opvee. But the company that makes it, Indivior, has found ...