The growth factors that are responsible for the survival, maintenance, and regeneration of specific neurons are NGF, GDNF, and BDNF. Such growth factors make them therapeutics for ...

NGF activates TrkA on sensory nerves, upregulating the expression of pronociceptive molecules, such as capsaicin receptor (TRPV1), BDNF, and neuropeptides (substance P and CGRP), in sensory ...

while stimulating brain-derived neurotrophic factor (BDNF, a protein involved in in improving brain cell growth and vital for long-term memory and cognitive function). Nerve growth factor (NGF ...

Future Neurology. 2013;8(2):175-192. BDNF and NGF are neurotrophins that promote neuronal survival and plasticity through binding to their specific high-affinity tyrosine kinase receptors (TrkB ...

The hope that nerve growth factor (NGF) inhibitors could be an alternative to opioid for pain relief has finally been extinguished with the news that Regeneron had abandoned the last drug in the ...

Antibodies included biotin-conjugated anti-BDNF (5 mg/L) chicken polyclonal (A&D system, Minneapolis, MN), anti-NGF (1:100) rabbit monoclonal (Cell Signaling, Danvers, MA), and anti-p75 NTR (1:100 ...

Furthermore, PBMCs obtained during the treatment period produced significantly more BDNF and PDGF-BB. Conclusion: These results are consistent with an immunomodulatory effect of testosterone ...

ACD856 has the potential to be the first drug in a new category of Alzheimer's drugs - positive allosteric modulators of Trk receptors (Trk-PAMs), which increase BDNF and NGF signaling.

while stimulating brain-derived neurotrophic factor (BDNF, a protein involved in in improving brain cell growth and vital for long-term memory and cognitive function). Nerve growth factor (NGF) levels ...

ACD856 has the potential to be the first drug in a new category of Alzheimer's drugs - positive allosteric modulators of Trk receptors (Trk-PAMs), which increase BDNF and NGF signaling.