This small particle acts as the digestive tract of the living cell. Its enzymes dissolve the substances ingested by the cell and under certain circumstances can dissolve the cell itself ...

Each lysosome, about 0.1 to 1.2 micrometers in ... say that it's a process of self-cleaning that happens within the human ...

Tan used a lentivirus to express an enzyme called Turbo-ID in human cells, which sticks a biotin tag onto any protein within a ten-nanometer radius. Using a version of the enzyme which localizes to ...

This bubble then merges with the lysosome, where the contents are ... leading to the buildup of waste inside cells and human diseases. "We're excited about the potential of this research to ...

On screening human cells to identify proteins that shuttled from the cytosol ... because their activation coincided with genes that increased lysosome production. TFEB is also an ancient regulator of ...

In brief, autophagy is a ubiquitous process in eukaryotic cells that results in the breakdown of cytoplasm within the lysosome in response ... role for autophagy in human pathophysiology.

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

Organelles are entities within a eukaryotic cell that have a specialised function ... mitochondria, vacuoles or lysosomes, and chloroplasts (in plants). Nellie is a user-friendly tool that ...