They function in vivo to repair a break in E. coli tRNA Lys triggered by phage-activation of a latent host-encoded anticodon nuclease PrrC. PrrC specifically incises tRNA Lys at a single site in the ...
The modified tRNA base 2-thiouridine is required for many steps in translation. Surprisingly, the biosynthesis of this simple derivative requires a minimum of four sulfur transfer reactions ...
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