The paper is published in the journal Cell Reports. The researchers found that ATP-citrate lyase (ACLY), an enzyme involved in converting citrate to acetyl-CoA, plays a critical role in activating ...

The paper is published in the journal Molecular Cell. "Until now, we only knew of one enzyme, selenocysteine lyase (SCLY), which was responsible for releasing the selenium atom from selenocysteine ...

Adenylosuccinate Lyase (ADSL): An enzyme involved in the de novo synthesis of purines, crucial for producing purine nucleotides. Purine Metabolism: The biochemical processes that synthesize and ...

which appears to influence substrate preference and the efficiency of the lyase reaction. Mutations at this site can alter the enzyme's active site structure, affecting its catalytic activity[3].