While many chemists may long be familiar with LC-MS/MS for routine analysis, method development with compound optimization requires another set ... one needs to optimize LC conditions including the ...

9 This article, therefore, outlines the performance of a targeted method utilizing the QSight ® 220 liquid chromatography triple quadrupole mass spectrometer (LC-MS/MS). The article looks at the ...

An LC–MS/MS method for the quantitative determination of vitamin D3 ... The mobile phase operated at a flow rate of 1200 μL/min and consisted of 0.1% (v/v) formic acid in water as solvent A and ...

Drs Dawn Dufield and Dominic Warrino, KCAS Bioanalytical and Biomarker Services, share expertise on using Hybrid LC-MS versus LBA for bioanalytical analysis. Selecting the right bioanalytical method ...