Pretreatment with the chemical chaperone 4-phenylbutyric acid, the JNK inhibitor SP600125, or the antioxidant N-acetylcysteine alleviated insulin resistance, demonstrating that ozone sequentially ...
Mechanistically, the essential role of JNK in hepatocarcinogenesis has been partially explained via its activation through phosphorylation of c-Jun. As a well characterized oncogene, c-Jun is ...
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