The IGFs can bind to six well-characterized soluble IGF-binding proteins (IGFBPs) as well as to two transmembrane tyrosine-kinase-linked receptors—the insulin receptor (IR) and the IGF1 receptor ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

“Endothelial cells are full of insulin receptors,” says Stefan Offermanns, who led the study. When the endothelial cells sense elevated insulin, they dilate blood vessels, increasing tissue ...