Researchers used advanced cryo-electron microscopy to capture atomic-level images of how glutamate, a key neurotransmitter, opens channels in brain cells.

NMDA receptors, members of the excitatory ionotropic glutamate receptor family, are essential to these processes. They regulate the strength of synaptic connections, playing a critical role in ...

Medically reviewed by Femi Aremu, PharmD Dementia is a loss of brain function that affects memory, thinking, judgment, ...

Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most ...

However, previous studies involving peripheral injection of excitatory amino acids have also found that NMDA or AMPA receptor antagonists completely eliminate glutamate-induced hypersensitivity 37,38.

you can kind of know that NMDA, which is actually a glutamate receptor — it’s one of the two glutamate receptors and glutamate is the most common excitatory neuron in the brain.

NMDAR = N-methyl-D-aspartate receptor; VGKC = voltage-gated potassium channel a In some patients with paraneoplastic anti-NMDAR encephalitis, the possibilities of bacterial infections, HIV ...

These medications work by blocking N-methyl-D-aspartate (NMDA) receptors and reducing excess glutamate which can promote the death of neurons. They’re considered effective for managing symptoms ...