Even when CRISPR nucleases are directly delivered into cells, their large protein sizes present limitations. For example, the commonly used Cas9 is about 1,400 amino acid residues long. “It's like a ...

Genome editing is a powerful biotechnology tool that allows scientists to make precise changes to an organism's DNA. It involves the use of specialized enzymes, known as engineered nucleases or ...

Genome-editing technologies enable precise editing ... The ARCUS gene-editing platform is derived from the nuclease I-CreI of the green alga Chlamydomonas reinhardtii. This nuclease evolved ...

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing ...

T he core components of CRISPR-based genome-editing therapies are bacterial proteins called nucleases that can stimulate unwanted immune responses in people, increasing the chances of side effects ...

“The whole community of genome editing was absolutely excited, because it was so difficult to make zinc finger nucleases work specifically,” Boch explained. By contrast, with the TALE code cracked, ...

Recent research published in the journal Science Bulletin detailed the creation of a tool called ChCas12b that can accurately ...

Officials at ARM, ASGCT, and ISCT convened a small group of scientists, policy experts, religious leaders and patient ...

Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company utilizing its novel proprietary ARCUS® ...

Dana Carroll, "Genome Engineering with Zinc-Finger Nucleases," Genetics 188, no. 4 (2011): 773"782 Elena E. Perez et al., "Establishment of HIV-1 Resistance in CD4+ T cells by Genome Editing Using ...

About Precision BioSciences, Inc. Precision BioSciences, Inc. is a clinical stage gene editing company dedicated to improving life (DTIL) with its novel and proprietary ARCUS® genome editing ...