How do bacteria, lacking a nucleus, organize and pack their genome into the cell? Supercoiling enables this but forces a different kind of transcription and translation in prokaryotes. Aa Aa Aa ...

presents compelling experimental evidence supported by a theoretical model that the amount of chromosomal DNA can become limiting for the total rate of mRNA transcription and consequently protein ...

When Kostas Konstantinidis proved that many bacteria—like plants and animals—are organized into species, he upended a ...

Here, David Ussery from the Department of BioMedical Informatics, UAMS, details E. coli genome diversity, big data, and messy biology. New methods, we discover, allow for the comparison of millions of ...

Current optical and electron microscopy imaging techniques are not suited for measuring the dynamic characteristics of living ...

However, new findings from Konstantinidis and his team suggest otherwise, positing that bacteria not only form species but also maintain cohesion within these species through mechanisms that closely ...

In the December Nature Biotechnology Selinger et al. use an Escherichia coli oligonucleotide array with 30-base-pair resolution to detect antisense transcripts, new open reading frames (ORFs), and ...

coli genome. Here, we introduced the code used for promoter sequences ... Global transcriptional start site mapping using differential RNA sequencing reveals novel antisense RNAs in Escherichia coli, ...

In short, while bacteria may not have “sex lives” in the way humans do, their frequent DNA exchanges play a crucial role in ...

More information: Sofya K Garushyants et al, Mutational Signatures in Wild Type Escherichia coli Strains Reveal Predominance ...

Their main goal is to produce more bacteriophages by injecting their genome into a bacterial host ... bacteriophage resistance in the bacterium Escherichia coli. The methylase enzyme added ...

and Talya R. Davis **. "Genome-wide identification of H-NS controlled, temperature regulated genes in Escherichia coli K-12." J Bacteriol. 2009 Feb;191(3):1106–10. Epub 2008 Nov 14. White-Ziegler, ...