The “lock and key” model was first proposed in 1894. In this model, an enzyme’s active site is a specific shape, and only the substrate will fit into it, like a lock and key.

There are two theories explaining the enzyme-substrate interaction. In the lock-and-key model, the active site of an enzyme is precisely shaped to hold specific substrates.

In anger, she questions what is wrong with her lock and key. Alfred, the science app, responds by explaining how enzymes work in relation to the ‘lock and key’ model.

Transmission electron microscopy confirmed that the enzyme was located within the cavity of the DNA vault. The team then took this closed DNA vault containing aCt and mixed it with FITC-casein, a ...

The dynamics of large organic molecules on surfaces is, therefore, analogous to the dynamics of the so-called lock-and-key recognition between enzymes and the substrate on which they act 23.

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

In anger, she questions what is wrong with her lock and key. Alfred, the science app, responds by explaining how enzymes work in relation to the ‘lock and key’ model.