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Figure 1: The filled dynamic programming matrix for two DNA sequences, x = TTCATA and y = TGCTCGTA, for a scoring system of +5 for a match, −2 for a mismatch and −6 for each insertion or deletion.
The problem with dynamic scoring isn’t political. It’s actually a problem of computer programming that’s well known to experts in the field, Republicans and Democrats alike, but hard to ...
Dynamic programming algorithms for RNA folding are guaranteed to give the mathematically optimal structure. Any lack of prediction accuracy is more the scoring system's problem than the algorithm ...