Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of ...
We developed gel electrophoresis-based assays that could be used to easily score DNA condensation. In these assays, a large nicked DNA plasmid when bound by MukB migrated faster in the gel than the ...
Additional modeling studies showed that if the number of base pairs per protein monomer is increased (for example, to 10 base pairs per protein), many possibilities for DNA condensation may exist ...