Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway. Most of the proteins and glycoproteins that ...

The complement system, which consists of more than 30 plasma and cell-surface proteins, is activated by three pathways — the classical, lectin and alternative pathways — which lead to the ...

The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface. It only comes into effect when a high number of ...

A new study published on the preprint server bioRxiv* discusses the activation of the complement system ... including both the classical and the alternative pathways of lectins, thereby making ...

A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement system in human tissue, a discovery that could reshape the treatment of many rheumatic ...