This has spurred scientists to wonder whether enhancing the flow of CSF could boost brain health. But glymphatic vessels have previously only been identified deep in the neck, making them hard to ...

When the pattern was shown, this caused a rise in blood flow to the brain’s visual centres, as expected. When the screen went dark, blood flow reduced and CSF flow into the brain increased.

The study, published on October 31 in Science, is the first to illustrate that the brain's CSF pulses during sleep, and that these motions are closely tied with brain wave activity and blood flow ...

Large oscillations of CSF inflow to the brain appeared about every 20 seconds and were tightly coupled to functional magnetic resonance imaging (fMRI) signals of blood flow and ...

Earlier studies have suggested that CSF flow and slow-wave activity both help flush toxic, memory-impairing proteins from the brain. As people age, their brains often generate fewer slow waves.

The study - published in Science - is the first to illustrate that the brain’s CSF pulses during sleep, and that these motions are closely tied with brain wave activity and blood flow.

After the pattern was displayed, volunteers experienced a rise in their blood flow. The study further said that when the screen went dark, blood flow reduced and CSF flow into the brain increased.

“After stimulation, the older mice’s CSF flow was similar to that of younger mice [that hadn’t yet been massaged],” says Koh. In unpublished work, the team found similar results in monkeys.