CRISPR-Cas9 is a powerful gene editing tool that cuts ... design and cell-line selection to bioinformatic analysis of the screen results. What is CRISPR screening? The CRISPR-Cas9 technology ...

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

This study “harnesses CRISPR pooled screening technology to help us figure out where the functional regions in the noncoding genome [are],” he explained. Gersbach and colleagues created lentiviral ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

CRISPR/Cas9 remains the most powerful tool to generate ... To put it in numbers: with their previous vector, a CRISPR screen looking for all double knockouts of just 20 genes was estimated to ...

A research team investigates how genome editing can be harnessed to accelerate cassava breeding and improve key traits.

CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform.

Mammalian cell gene editing has extensively used RNA-guided CRISPR-Cas systems, which have shown great promise in the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...