Timothy was diagnosed with bulbar onset sporadic ALS, one of its most aggressive forms. In most cases ALS attacks the large muscle groups first, with a slow progression to fine motor skills, until the ...

Spinal bulbar muscular atrophy (SBMA) is a progressive genetic neuromuscular condition that affects motor neurons. Over time, it may cause symptoms such as difficulty speaking, swallowing ...

The observations of Kim et al. raise several questions. Why is PMA more common in men, whereas bulbar-onset ALS is more common in women? Why does PMA progress more slowly than the classic form of ALS?