The BMJ: Leading Medical Research, News, Education, Opinion
WEBUnless we confront antimicrobial resistance now, we risk the consequences of a post-antibiotic society. opinion. | Sep 26. World leaders commit to reduce deaths from antimicrobial resistance by 10% by 2030. Politicians are failing to prepare for next pandemic, warns head of European health agency. …
Paroxysmal atrial fibrillation - The BMJ
WEBDec 30, 2021 · Atrial fibrillation is the most commonly encountered cardiac arrhythmia in clinical practice (box 1). 7 Paroxysmal atrial fibrillation (PAF) is intermittent episodes of atrial fibrillation that terminate within seven days either spontaneously or with intervention. 8 This excludes atrial fibrillation that is triggered by transient causes such as ...
Impact of vaping on respiratory health | The BMJ
WEBJul 18, 2022 · Widespread uptake of vaping has signaled a sea change in the future of nicotine consumption. Vaping has grown in popularity over the past decade, in part propelled by innovations in vape pen design and nicotine flavoring. Teens and young adults have seen the biggest uptake in use of vape pens, which have superseded conventional cigarettes as the preferred modality of nicotine consumption.
Gout: diagnosis and management—summary of NICE guidance
WEBAug 30, 2022 · Measure the serum urate level in people with symptoms and signs of gout to confirm the clinical diagnosis (serum urate level ≥360 μmol/L (6 mg/dL)). If serum urate level is <360 μmol/L during a flare and gout is strongly suspected, repeat the serum urate level measurement at least two weeks after the flare has settled.
Interpreting iron studies | The BMJ
WEBJun 15, 2017 · What is included in iron studies? Ferritin—is the intracellular storage form of iron.A very small amount is found in serum. In inflammation, liver disease, and malignancy, ferritin levels can rise because ferritin is an acute phase protein.4 In these patients, ferritin can appear either falsely high or normal, when in reality stores are low. Serum iron—refers to ferric ions (Fe 3+) bound ...
Management of ulcerative colitis: summary of updated NICE …
WEBOct 28, 2019 · What’s new in the guidance. Ulcerative colitis is a chronic inflammatory disease of the rectum and colon characterised by mucosal inflammation, resulting in symptoms of diarrhoea (both soft stool and an increased frequency of defecation), rectal bleeding, an urgent need to defecate, and abdominal pain. …
The PRISMA 2020 statement: an updated guideline for reporting ...
WEBMar 29, 2021 · The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement ...
Strengthening the basics: public health responses to prevent the …
WEBNov 29, 2021 · Victoria Haldane and colleagues argue that to make covid-19 the last pandemic, public health responses to outbreaks must be strengthened, starting with their most basic functions The covid-19 pandemic has challenged countries to mount and sustain comprehensive public health responses that identify and control an emerging infectious hazard. These challenges have persisted into 2021 and likely ...
Postural hypotension - The BMJ
WEBApr 23, 2021 · Postural hypotension is a drop in blood pressure (≥20 mm Hg systolic and/or ≥10 mm Hg diastolic) that occurs within 3 minutes of standing. Test for it in people who have symptoms of lightheadedness or dizziness on changing from lying or sitting to standing posture or those with an unexplained fall. …
Interpreting an isolated raised serum alkaline phosphatase level in …
WEBApr 3, 2013 · The next step. A reasonable approach in adults with an isolated raised serum ALP level is therefore a careful medical and drug history (table ⇓) and physical examination.4 6 7 Key features include abdominal pain or swelling, unintentional weight loss, back pain, bone pain, clinical indicators of liver disease, congestive cardiac failure, and end stage chronic kidney disease.4 5 If patients ...